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. 2018 Jun 16;109(7):2243–2255. doi: 10.1111/cas.13650

Figure 5.

Figure 5

Rosiglitazone inhibits 4T1 tumor metastasis to the lung. A, Photographs of the lungs. B, Representative H&E‐stained lung sections and quantification of H&E‐stained lung metastasis (n = 6). Scale bar, 0.5 mm. Metastatic lung foci are highlighted by dashed lines. C, Representative microCT images of 4T1 mice (n = 6). Gross tumor volumes (red), lungs (pale purple) and bones (white) are delineated on every section of the CT scans. Scale bar, 2.5 mm. D, Immunohistochemical stain for F4/80 to indicate tumor‐associated macrophage infiltration in 4T1 primary tumor and lung metastasis (n = 6). Scale bars, 50 μm. Data are presented as mean ± SEM. Rosig, rosiglitazone. *P < .05, **P < .01; ns, non‐significant