Prescribed doses of greater or equal to 50-mg morphine equivalents
Personal history of previous overdose
History of substance use disorder or concurrent use of benzodiazepines
Relatives of family members with OUD in states where third party prescribing is allowed
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High-dose opioid therapy
Comorbidities
During opioid rotation
OUD
Recreational opioid use
Intravenous drug use
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