Table 1.

Selected examples of the O-cyanation/hetero oxy-Cope rearrangement.^a

^aCited yields and isomeric ratios are of isolated material by column chromatography.

^bYield in parenthesis was determined by ¹H NMR analysis of the crude reaction mixture with CH₂Br₂ an internal standard.

^cThe reaction exhibited 6.4:1 selectivity, but the minor product came with inseparable impurities. The yield reported here is of the major isomer only.

^dYield in the bracket is the isolated yield of a gram-scale reaction.