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Experimental setup for the in vivo drug delivery experiments. (a) The animal was placed on its side on the MR-HIFU platform with one thigh in the path of a focused ultrasound beam. (b) A transverse MR image through the thigh shows the location of heating in the dashed circle. (c) A sagittal MR image along the path of the ultrasound beam shows the location of heating in a perpendicular plane. The relationship between both images is illustrated with the white dashed lines.
