Table 3.
Neonatal outcomes by fertility treatments
| Neonatal outcomes | Group 1: IVF/ICSI (n = 310) | Group 2: IUI/OI (n = 150) | p value |
|---|---|---|---|
| Female infant | 162 (53.5) | 77 (51.7) | 0.72 |
| Birth weight | 0.009 | ||
| < 2000 g | 89 (29.4) | 28 (18.8) | |
| 2000–2499 g | 104 (34.3) | 46 (30.9) | |
| ≥ 2500 g | 110 (36.3) | 75 (50.3) | |
| Birth weight (g) mean (SD) | 2278 (± 605) | 2427 (± 519) | 0.01 |
| Composite neonatal morbidity | 36 (11.9) | 9 (6.0) | 0.051 |
| Small for gestational age | 26 (8.6) | 7 (4.7) | 0.14 |
| Apgar ≤ 3 at 1 min | 21 (7.0) | 5 (3.4) | 0.12 |
| Apgar ≤3 at 5 min | 6 (2.0) | 1 (0.7) | 0.43 |
| NICU Admission | 154 (50.8) | 57 (38.3) | 0.01 |
| Retinopathy of prematurity | 0 (0) | 3 (2.0) | 0.04 |
| Intraventricular hemorrhage III/IV | 1 (0.3) | 0 (0) | 0.99 |
| Periventricular leukomalacia | 1 (0.3) | 0 (0) | 0.99 |
| Necrotizing enterocolitis stage II/III | 1 (0.3) | 0 (0) | 0.99 |
| Respiratory distress syndrome | 28 (9.2) | 9 (6.0) | 0.24 |
| Bronchopulmonary dysplasia | 2 (0.7) | 6 (4.0) | 0.02 |
| Sepsis | 4 (1.3) | 3 (2.0) | 0.69 |
| Mechanical ventilation | 22 (7.3) | 11 (7.4) | 0.96 |
| Transient tachypnea of the newborn | 49 (16.3) | 19 (12.8) | 0.33 |
| Vanishing fetus | 24 (7.7) | 6 (4.0) | 0.13 |
| Definite seizure | 1 (0.3) | 1 (0.7) | 0.55 |
| Death before discharge | 5 (1.7) | 1 (0.7) | 0.67 |
| Stillbirth | 5 (1.6) | 0 (0) | 0.18 |
| Meconium aspiration syndrome | 1 (0.3) | 0 (0) | 0.99 |
Data are presented as n (%)
NICU, neonatal intensive care unit; CNM, respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, periventricular leukomalacia, bronchopulmonary dysplasia, and/or death prior to discharge