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. 2018 Mar 9;35(6):1011–1017. doi: 10.1007/s10815-018-1149-x

Table 3.

Neonatal outcomes by fertility treatments

Neonatal outcomes Group 1: IVF/ICSI (n = 310) Group 2: IUI/OI (n = 150) p value
Female infant 162 (53.5) 77 (51.7) 0.72
Birth weight 0.009
 < 2000 g 89 (29.4) 28 (18.8)
 2000–2499 g 104 (34.3) 46 (30.9)
 ≥ 2500 g 110 (36.3) 75 (50.3)
Birth weight (g) mean (SD) 2278 (± 605) 2427 (± 519) 0.01
Composite neonatal morbidity 36 (11.9) 9 (6.0) 0.051
Small for gestational age 26 (8.6) 7 (4.7) 0.14
Apgar ≤ 3 at 1 min 21 (7.0) 5 (3.4) 0.12
Apgar ≤3 at 5 min 6 (2.0) 1 (0.7) 0.43
NICU Admission 154 (50.8) 57 (38.3) 0.01
Retinopathy of prematurity 0 (0) 3 (2.0) 0.04
Intraventricular hemorrhage III/IV 1 (0.3) 0 (0) 0.99
Periventricular leukomalacia 1 (0.3) 0 (0) 0.99
Necrotizing enterocolitis stage II/III 1 (0.3) 0 (0) 0.99
Respiratory distress syndrome 28 (9.2) 9 (6.0) 0.24
Bronchopulmonary dysplasia 2 (0.7) 6 (4.0) 0.02
Sepsis 4 (1.3) 3 (2.0) 0.69
Mechanical ventilation 22 (7.3) 11 (7.4) 0.96
Transient tachypnea of the newborn 49 (16.3) 19 (12.8) 0.33
Vanishing fetus 24 (7.7) 6 (4.0) 0.13
Definite seizure 1 (0.3) 1 (0.7) 0.55
Death before discharge 5 (1.7) 1 (0.7) 0.67
Stillbirth 5 (1.6) 0 (0) 0.18
Meconium aspiration syndrome 1 (0.3) 0 (0) 0.99

Data are presented as n (%)

NICU, neonatal intensive care unit; CNM, respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, periventricular leukomalacia, bronchopulmonary dysplasia, and/or death prior to discharge