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. 2018 Jul 3;8:9993. doi: 10.1038/s41598-018-28404-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Migration of tree shrew’s PBMCs depended on CXCL10-CXCR3 function. (a) Quantification of in vitro transmigration of tree shrew’s PBMCs induced by recombinant human CXCL10 (n = 9 wells per group, *p < 0.05, **p < 0.01, ***p < 0.001). (b) Targeting CXCR3 by NBI74330 efficiently blocked hCXCL10-induced in vitro transmigration of tree shrew’s PBMCs (n = 9 wells per group, *p < 0.05, ***p < 0.001). Error bars indicate SEM.