Skip to main content
. 2018 Jul 3;9(7):741. doi: 10.1038/s41419-018-0782-8

Fig. 2. SOX17 suppressed cervical carcinoma tumor growth in vivo.

Fig. 2

SOX17 expression in human cervical cancer cell lines was detected using immunocytochemistry (a) and Western blotting (b). Stably transfected cell lines were identified by western blotting. c HeLa-GFP and HeLa-SOX17 cells; SiHa-GFP and SiHa-SOX17 cells; HeLa-shControl and HeLa-shSOX17 cells; SiHa-shControl and SiHa- shSOX17 cells. Female nude mice were injected with the SOX17-modified cervical cancer cells (left) and control cells (right) (d, g, j, m). Tumor growth curves were calculated after injection based on monitoring performed every 3 days and the xenograft tumors were dissociated and weighed at the end of the experiment. e, f HeLa-GFP and HeLa-SOX17 cells. h, i SiHa-GFP and SiHa-SOX17 cells. k, l HeLa-shControl and HeLa-shSOX17 cells. n, o SiHa-shControl and SiHa-shSOX17 cells. Values are shown as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001