Table 1.
Minimum inhibitory concentrations of tested antimicrobial agents for the studied bacterial isolates
| Species | MIC (µg/ml) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CST | PB | TET | MEM | TAZ | AMC | SXT | AN | GEN | STR | FFC | CIP | |
| K.pneumoniae KP91 | 16 | 8 | >256 | 0.06 | 16 | 32/16 | 16 | >256 | 512 | 256 | 256 | 256 |
| E. coli J53 + pKP91 | 4 | 4 | 1 | 0.015 | 0.5 | 4/2 | 0.5 | 1 | <0.125 | 4 | 4 | 0.015 |
| E. coli J53 | 0.25 | 0.25 | 1 | 0.03 | 0.5 | 4/2 | 0.5 | 1 | <0.125 | 4 | 4 | 0.015 |
| DH5ɑ + pUC19-mcr-8 | 1 | 0.5 | – | – | – | – | – | – | – | – | – | – |
| DH5ɑ + pUC19 | 0.25 | 0.25 | – | – | – | – | – | – | – | – | – | – |
| K. pneumoniae_ | 8 | 8 | – | – | – | – | – | – | – | – | – | – |
| ATCC13883+pUC19-mcr-8 | ||||||||||||
| K. pneumoniae_ | 1 | 2 | – | – | – | – | – | – | – | – | – | – |
| ATCC13883+pUC19 | ||||||||||||
Antimicrobial susceptibilities, reported as MIC (µg/ml), were interpreted as resistant (bold) or susceptible (plain text) in accordance with established breakpoints. CST colistin, PB polymyxin B, TET tetracycline, MEM meropenem, TAZ ceftazidime, AMC amoxicillin-clavulanate, SXT trimethoprim-sulfamethoxazole, AN amikacin, GEN gentamycin, STR streptomycin, FFC florfenicol, CIP ciprofloxacin. “–” indicates that the MIC was not measured