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. 2018 Jul 3;8:10072. doi: 10.1038/s41598-018-28117-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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SKMC-S and SKMC-T have different myokine profiles under control conditions and after TNF-alpha treatment. Cytokines secreted in the conditioned media of SKMC-S (open bars) and SKMC-T (closed bars) cells in control condition or in the presence of TNF-alpha in the medium for 24 h, n = 4. GRO1 Oncogene (GRO; (A)); Interleukin-6 (IL-6; (B)), Monocyte Chemotactic Protein 1 (MCP1; (C)), Monocyte Chemotactic Protein 3 (MCP3; (D)), Regulated on Activation, Normal T Cell Expressed and Secreted (RANTES; (E)), Tumor necrosis factor alpha (TNFa; (F)), Angiogenin (G), osteoprotegerin (OPG; (H)). *p < 0.05 for the indicated comparisons as tested by ANOVA followed by Bonferroni post hoc test.