Table 2.
Univariate quantitative analysis of metabolites commonly detected by all platforms
GCMS | LCMS | NMR | ||||
---|---|---|---|---|---|---|
Fold change | t-test | Fold change | t-test | Fold change | t-test | |
Creatine | 2.05 | 0.0015 | 2.50 | 0.0476 | 2.17 | 0.0003 |
Fumarate | 2.56 | 0.0143 | 2.34 | 0.0000 | 1.53 | 0.0114 |
Glutamate | 1.72 | 0.0013 | 1.98 | 0.0000 | 1.53 | 0.0096 |
Glutamine | 6.52 | 0.0009 | 7.12 | 0.0000 | 6.60 | 0.0129 |
Lactic acid | 3.08 | 0.0038 | 3.96 | 0.0058 | 4.30 | 0.0275 |
Myo-inositol | 2.56 | 0.0011 | 1.61 | 0.0220 | 1.68 | 0.0034 |
HGT-1 cancer cells were treated for 36 h and collected for biochemical analyses. The identified metabolites are listed in alphabetical order. The fold-changes and the p-values (Student t-test, p < 0.05) are shown