Table 4.
Regression models to assess the effect of age on anti-α-Gal antibody levels and interaction with site in infants (1.5–3 months old) and children (5–17 months old) from Manhiça and Kintampo.
| Coefficient | Std. Error | t value | Pr(>|t|) | |
|---|---|---|---|---|
| IgM | ||||
| Infants | ||||
| (Intercept) | 3.6632 | 0.5562 | 6.587 | 1.83E-09 |
| Age | 8.0381 | 3.8208 | 2.104 | 0.0378 |
| Manhiça | 0.3859 | 0.9327 | 0.414 | 0.6799 |
| Age-site (Manhiça) interaction | −1.2675 | 5.6345 | −0.225 | 0.8225 |
| IgG | ||||
| (Intercept) | 5.969 | 0.4852 | 12.302 | <2e-16 |
| Age | −3.1377 | 3.3335 | −0.941 | 0.349 |
| Manhiça | −0.2149 | 0.8137 | −0.264 | 0.792 |
| Age-site (Manhiça) interaction | 3.1261 | 4.9158 | 0.636 | 0.526 |
| IgM | ||||
| Children | ||||
| (Intercept) | 6.0856 | 0.2015 | 30.201 | <2e-16 |
| Age | 0.5762 | 0.2035 | 2.831 | 0.00584 |
| Manhiça | −0.2545 | 0.2701 | −0.942 | 0.34871 |
| Age-site (Manhiça) interaction | 0.3149 | 0.2721 | 1.158 | 0.25042 |
| IgG | ||||
| (Intercept) | 4.5273 | 0.3568 | 12.689 | <2e-16 |
| Age | 0.9355 | 0.3604 | 2.596 | 0.0112 |
| Manhiça | 0.1022 | 0.4782 | 0.214 | 0.8313 |
| Age-site (Manhiça) interaction | 0.4787 | 0.4817 | 0.994 | 0.3233 |
Data correspond to samples collected at baseline (M0) from participants in the RTS,S phase 3 clinical trial.