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. 2018 Jul 3;8:10010. doi: 10.1038/s41598-018-28263-7

Figure 2.

Figure 2

Summary of in vitro agonist potencies. (a) Scatterplot of in vitro agonist potencies by IP3 accumulation in SUCNR1 transfected HEK-293 cells of the compounds in Tables 15 on the hSUCNR1 and mSUCNR1 receptor. (b,c) Dose-response curves for succinate and selected compounds (3, 21 and 31) on hSUCNR1 and mSUCNR1.