Table 1.
Body weight gain, food intake, liver (ALP and AST) and kidney (creatinine) function test, triglyceride (TG), and total cholesterol (TC) levels in the experimental animals.
| Parameters | Normal | HIET | HFD | HFD + HIET |
|---|---|---|---|---|
| Body weight gain (%) | 5.35 ± 1.20 | 5.11 ± 0.81 | 12.29 ± 0.82* | 7.85 ± 0.86# |
| Food intake (g/mouse/day) | 2.54 ± 0.03 | 2.52 ± 0.014 | 2.5 ± 0.01 | 2.52 ± 0.004 |
| ALP (U/L) | 38.88 ± 2.29 | 35.23 ± 1.64 | 38.93 ± 4.34 | 37.06 ± 3.83 |
| AST (U/L) | 27.81 ± 1.27 | 32.01 ± 6.26 | 34.92 ± 5.33 | 34.56 ± 2.11 |
| Creatinine (mg/dL) | 0.047 ± 0.0015 | 0.051 ± 0.0039 | 0.049 ± 0.0047 | 0.046 ± 0.0021 |
| Triglyceride (mM) | 0.57 ± 0.009 | 0.66 ± 0.03 | 1.9 ± 0.209* | 1.18 ± 0.062# |
| Total Cholesterol (mM) | 0.28 ± 0.019 | 0.32 ± 0.047 | 0.44 ± 0.059* | 0.34 ± 0.055 |
Both normal and HFD-fed mice were gavaged with either olive oil or HIET (20 µg/kg BW, daily for 8 wks) respectively. Values are mean ± SE. “*” Denotes the significant difference from Normal (*p < 0.05) and “#” denotes the significant difference from HFD mice (#p < 0.05).