Figure 6.

MR imaging of GIC-derived xenograft tumors.

(A) Photograph of a coronally sectioned brain with xenograft tumor and corresponding MR images displayed scattered contrast enhancement and widespread pathological T₂-hyperintensity in the transplanted hemisphere. The T₂-hyperintensity was found along the corpus callosum extending into the non-transplanted hemisphere (yellow arrowhead). (B) Coronal MR slices showing T₂-signal abnormality (red arrowheads) involved several regions outside the striatal tumor core: thalamus, cortical areas of the convexity, parts of occipital lobes and white matter structures, whereas the hippocampi in the transplanted (white arrow with solid line) and non-transplanted hemispheres (white arrow with dashed line) were spared. Red asterisks mark dilated ventricles.

Abbreviations: cc, corpus callosum; HPC, hippocampus; Sep, septum; STR, striatum; TC, tumor core; TH, thalamus.