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. 2018 May 21;20(7):643–656. doi: 10.1016/j.neo.2018.04.001

Table 1B.

Brain-Wide Distribution and Density of Immunolabeled Tumor Cells

The Five-Point Grading Scale is Defined in Table 1A

Transplanted hemisphere
Non-transplanted hemisphere
Brain regions (BRs) hMit Vim hMit Vim
Tumor Core Non-adjacent BRs
Caudate Putamen ++++ +++ ++ ++
Globus Pallidus ++++ ++++ ++ +
Adjacent BRs
Ventral striatum +++ ++ + +
Thamalus +++ ++ + +
Hypothalamus + +
Amygdala +
Septal nuclei (medial and lateral) +++ +++ ++ ++
Subependymal space of the Lateral ventricle ++++ ++++ +++ +++
Cortical areas
Limbic cx ++ ++ ++ +
Cingulate cx ++ + + +
Motor cx +++ ++ ++ +
Somatosensory cx +++ ++ ++ +
Insular cx +++ +++ + +
Auditory cx ++ ++ +
Visual cx ++ ++ +
Piriform cx +++ ++
Parahippocampal white matter
Fornix +++ +++ +++ +++
Fimbriae +++ +++ +++ ++
Hippocampal Commisure +++ +++ +++ +++
Alveus +++ +++ ++ ++
Hippocampal formation
CA1–3 + +
Dentate Gyrus + +
Subiculum + + +
Non-adjacent BRs
Subpial space over
the convexities +++ +++ + +
Pons ++ ++ ++ ++
Cerebellar cortex (+) (+) (+) (+)



White matter tracts
Lateral olfactory tract +++ ++
Anterior Commisure (A&P) +++ +++ ++ ++
Corpus callosum
Truncus ++++ ++++ ++++ ++++
External capsule ++++ ++++ +++ +++
Internal capsule +++ +++ ++ ++
Optic pathway
Optic nerve +++ +++ +++ ++
Optic chiasm ++++ +++ ++++ +++
Optic tract ++++ ++++ ++ ++
Optic nerve layer of superior colliculus ++ +
Cerebral peduncle ++++ ++++ ++ ++
Spinocerebellar tracts +++ +++ + +
Pyramidal tracts +++ +++ ++ ++
Cerebellar peduncles ++ ++ + +

Stratum oriens of CA: hMit ++/Vim+/hMit +/Vim+.