Fig. 6. miR-374b promotes the expressions of PI3K, and Akt and inhibits the expression of PTEN.
(A) MiR-374b level and mRNA levels of PTEN, PI3K and Akt by RT-qPCR. (B) Protein levels of PTEN, PI3K and Akt by western blotting; *p < 0.05, compared with the normal group; &p < 0.05 compared with the blank and NC groups; miR-374b, microRNA-374b; NC, negative control; RT-qPCR, reverse-transcription quantitative polymerase chain reaction; mean ± standard deviation; the t test was used to analyze data; n = 3.
