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(A) MAP clones of the signal sequence deletion and of missense mutations replacing the integrin motif from RGD into RDE in MAP1203. A signal sequence deletion and RCE mutation clones were constructed to identify the role of each domain of MAP1203. (B) Underlined regions indicate sequence of interest, and amino acids in red indicate the sequence deleted or mutated from the native MAP1203 gene. WT, (wild-type) native gene; RCE, mutated RGD binding domain; SS, signal sequence.
