Table 2.
Control | COPD-stable | COPD-exacerbation | Shapiro-Wilk | Levene’s test | p value | Jonckheere-Terpstra p value | |
---|---|---|---|---|---|---|---|
Nrf2, ng/mL | 12.71 ± 2.08 | 14.08 ± 1.87 | 15.22 ± 3.05 | 0.06 | 0.06 | 0.006a | 0.002 |
IL-6, pg/mL | 10.62 ± 5.20 | 12.34 ± 6.85 | 25.58 ± 32.19 | < 0.001 | < 0.001 | 0.653b | - |
SP-D, pg/mL | 85.13 ± 41.45 | 102.32 ± 70.01 | 162.03 ± 128.73 | < 0.001 | < 0.001 | 0.124b | - |
CRP, mg/dL | 1.55 ± 3.26 | 2.87 ± 4.14 | 5.15 ± 6.17 | < 0.001 | 0.080 | 0.001b | < 0.001 |
Values are presented as mean ± SD.
Nrf2, nuclear factor erythroid 2-related factor 2; IL-6, interleukin 6; SP-D, surfactant protein D; CRP, C-reactive protein; COPD, chronic obstructive pulmonary disease.
Analysis of variance.
Kruskal-Wallis test.