Table 1.
Demographic and disease variables at enrollment.
TEDDY children N=54 |
Community controls N=54 |
P-value | |
---|---|---|---|
Age at diagnosis (years) | 6.2±1.7 | 6.6 ±1.8 | <0.001 |
Gender (female), N (%) | 25 (46) | 32 (59) | 0.26 |
Family history of diabetes, N (%) | 10 (19) | 5 (9) | 0.23 |
HLA DR3/4, DQB1*0302*, N (%) | 32 (59) | 4 (10) | <0.001 |
Body mass indexa | 16.2 ±2.2 | 15.3±2.4 | 0.09 |
Diabetes symptoms, N (%) | 25 (51) | 50 (98) | <0.001 |
HbA1c at diagnosis % (mmol/mol) | 6.8 ±1.2 | 10.5 ±2.2 | <0.001 |
(51 ± 13) | (91 ± 24) | ||
Diabetic ketoacidosis, N (%) | 0 (0) | 8 (16%) | 0.003b |
Notes: Paired t-tests were used for continuous variables; McNemar’s test was used for binary variables. Mean +/− standard deviations are shown unless otherwise specified.
Data was missing in some subjects.
McNemar’s test was not feasible, thus Fisher’s exact test was used.