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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Mol Cancer Res. 2018 Mar 28;16(7):1138–1148. doi: 10.1158/1541-7786.MCR-17-0606

Figure 3. Akt/β-catenin/survivin signaling pathways downregulated by miR-342 and miR-363.

Figure 3

(A) Representative Western blot showing the relative expression of Runx2, survivin, and p-Akt in CAG cells transfected with miR-Scramble control, miR-342, miR-363, or miR-342+363 (left). Survivin and p-Akt expression levels were quantified and normalized to β-actin levels using ImageJ software (right). (B)Relative expression of Wnt-signaling pathway components β-catenin and GSK3β in CAG cells transfected with miR-Scramble control or miR-342, miR-363, or miR-342+363 mimics, measured by RT-qPCR. The P values were obtained by one-way ANOVA followed by Tukey-Kramer post hoc test (ns: non-significant; *P<0.05; **P<0.005; ***P<0.0001).