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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Neurochem. 2018 Apr 22;145(6):436–448. doi: 10.1111/jnc.14331

Fig. 2.

Fig. 2

Summary data CNO effects on MSN firing rate in DREADD negative and positive mice. (a) Paired before-after scatter plot showing a total lack of 2.5 mg/kg CNO effect on the spike firing rate of all the 19 MSNs recorded in D2 Gs-DREADD negative mice (n=2). (b) Paired before-after scatter plot showing that CNO clearly increased the spike firing rate of the 27 of the 54 MSNs recorded in D2 Gs-DREADD positive mice (n=3). The other 27 MSNs showed no change and are described in Fig. S4. (c) Scatter plot of the ratio of CNO firing rate/basal firing rate (i.e. normalized firing rate) showing CNO effects on MSN firing in D2 Gs-DREADD negative and positive mice. ***, p<0.001, paired t-test.