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. Author manuscript; available in PMC: 2019 Jun 10.
Published in final edited form as: J Neurochem. 2018 Jun 10;145(6):489–503. doi: 10.1111/jnc.14330

Figure 5. CSF auto-antibodies to α-syn are higher in Parkinson’s disease patients as compared to healthy controls.

Figure 5

(A) Levels of α-syn AAbs were significantly higher in CSF from PD patients (0.681 ± 0.50) as compared to CSF from HC (0.444 ± 0.36) (t143 = 2.98, p = 0.003). (B) Male HC had higher levels (0.537 ± 0.41) as compared to female HC (0.385 ± 0.33), which was not statistically significant (p = 0.14). (B) Male PD patients also had higher levels (0.702 ± 0.53) as compared to female PD patients (0.629 ± 0.44), which was not statistically significant (p = 0.53). Each data point depicts mean ± standard deviation of three samples per assay, each assay having three technical replicates (n=9 wells). Horizontal lines indicate mean and standard deviations.