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. Author manuscript; available in PMC: 2019 Jun 10.
Published in final edited form as: J Neurochem. 2018 Jun 10;145(6):489–503. doi: 10.1111/jnc.14330

Figure 7. Higher levels of α-syn auto-antibodies in CSF correlate with lower global cognitive performance.

Figure 7

Higher levels of CSF α-syn AAbs significantly correlated with lower total score on the MoCA (r = −0.22, p = 0.014), which remained significant when controlled for age and education (see text). In contrast, there was no significant correlation between serum α-syn AAb level and total MoCA score (p = 0.21). Each data point depicts mean of three samples per assay, each assay having three technical replicates (n=9 wells). Each serum data point depicts un-adjusted values. Regression line and 95% confidence band shown.