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. Author manuscript; available in PMC: 2019 Jul 3.
Published in final edited form as: Biochemistry. 2018 May 18;57(26):3916–3924. doi: 10.1021/acs.biochem.8b00367

Figure 3.

Figure 3

Chemical structure of HPB and stereoview of the superposition of the experimentally determined structure of the HDAC6–HPB complex (PDB 5WGK; blue) with a model of HPB in the same conformation with its phenylhydroxamate moiety superimposed with that observed in the HDAC6–1 complex. Phenylhydroxamate 1 is shown in yellow while the modeled HPB cap is shown in orange.