Skip to main content
. 2018 Jul 3;9(4):e01018-18. doi: 10.1128/mBio.01018-18

TABLE 1 .

Effects of translational errors on microbial stress resistance

Translational error(s) Stress condition(s) Organism(s) Fitness Reference(s)
Ile → norvaline Amino acid starvation Escherichia coli Gain 69
Ile → Val Amino acid starvation Acinetobacter baylyi Gain 70
Phe → meta-Tyr Amino acid starvation Escherichia coli Loss 67
Phe → Tyr Amino acid starvation Saccharomyces cerevisiae Loss 68
Gln → Glu; Asn → Asp Antibiotics Mycobacteria Gain 34, 55
Ile → Val Antibiotics Escherichia coli Gain 82
Met misincorporation Antibiotics Escherichia coli Gain 83
CUG codon ambiguity Antifungal drugs Candida albicans Gain 81
Arg → canavanine Heat stress Saccharomyces cerevisiae Gain 84, 85
CUG codon ambiguity Oxidative and osmotic stresses Saccharomyces cerevisiae Gain 72
Global mistranslation Oxidative stress Escherichia coli Gain 27, 71
Stop codon readthrough Various stresses Saccharomyces cerevisiae Gain/loss 73, 86
Ile → Val Sporulation Bacillus subtilis Loss 87