Table 2.

Brain volumes and white matter damage.

	pwMS (n = 29)	HCs (n = 18)	Effect size (η2)	p	p corr.
NWMV, ml	682.55 (46.91)	699.07 (39.36)	0.033	0.219	0.219
NCGMV, ml	780.47 (76.20)	839.46 (59.41)	0.148	0.008	0.009
NDGMV, ml	58.80 (6.88)	65.08 (4.59)	0.207	0.001	0.002
NLV, ml	22.46 (15.99)	–	–	–	–
WM damage
Whole brain average FA	0.33 (0.03)a	0.36 (0.02)	0.335	< 0.001	< 0.001
Severity score
Average Z-score skeleton	−0.61 (0.50)a	0.00 (0.34)	0.321	< 0.001	< 0.001
Extent score
Number of affected voxels	3430.30 (5115.74)a	21.90 (55.86)	0.822	< 0.001	< 0.001
(%)	(2.87%)	(0.02%)

Displayed data are mean (standard deviation).

HCs = healthy controls; NCGMV = normalized cortical grey matter volume; NDGMV = normalized deep grey matter volume; NLV = normalized lesion volume; NWMV = normalized white matter volume; WM = white matter; p corr. = false discovery rate corrected p-values; pwMS = people with multiple sclerosis.

^an = 27.