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. 2018 Jul 4;18:105. doi: 10.1186/s12876-018-0833-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — SPARCL1 is downregulated in human gastric GIST. The protein expression of SPARCL1 was determined by RT-qPCR and western blot with β-actin as a loading control. a Relative SPARCL1 mRNA level was significantly decreased in gastric GSIT with HGM as compared with those with LGM (**P < 0.05), while no statistical significance was noted between matched normal tissues from HGM and LGM (*P > 0.05); b, c A significant reduced expression of SPARCL1 in gastric GIST with HGM compared to those with LGM was determined by western blot analysis (**P < 0.05). N1~N2 for adjacent normal tissue of LGM, while N3~N4 for adjacent tissue of HGM. The bars represent mean ± SD (n = 4)