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Permeability coefficients of liposome formulations at 37 °C, 42 °C, and 37 °C with exposure to 760 nm laser illumination. Calculations made based on rate constants generated from first order rate equation curve fit to release data.
| Permeability Coefficient, P (10-12 cm/s) | |||
|---|---|---|---|
| 37 oC | 42 oC | Laser | |
| Doxil Uncoated (DU) | 10 | 0 | 50 |
| Doxil Gold-Coated (DC) | 20 | 10 | 90 |
| Liposomes Uncoated (LU) | 30 | 2600 | 80 |
| Liposomes Gold-Coated (LC) | 70 | 3700 | 60000 |
