Table 3.

Lifetime comorbidity of anxiety disorders in bipolar disorder I and bipolar disorder II.

Lifetime Comorbidity	BD I				BD II
	No of studies	No of Patients	Prevalence % (CI)	References	No of studies	No of patients	Prevalence % (CI)	References
Any anxiety disorder	21	5,842	38 (31–45)	(13, 16, 17, 34, 42, 46, 51, 56, 76, 87, 90, 95, 98, 99, 101, 103, 105, 106, 109, 110, 161)	11	2,171	34 (25–45)	(13, 27, 42, 55, 90, 98, 99, 105, 106, 109, 162)
Panic disorder	26	5,831	15 (11–19)	(9, 11, 13, 16–18, 34, 42, 46, 52, 76, 84, 90, 95, 98, 99, 103, 106, 109, 112, 121, 125, 129, 134, 161, 163)	15	1,823	15 (11–20)	(9, 11, 13, 27, 42, 52, 90, 98, 99, 106, 109, 121, 129, 136, 163)
Obsessive compulsive disorder	21	4,133	8 (6–12)	(9, 11, 13, 16, 17, 34, 42, 46, 76, 84, 90, 95, 98, 99, 106, 112, 125, 129, 134, 161, 163)	12	1,320	10 (7–14)	(9, 11, 13, 27, 42, 90, 98, 99, 106, 129, 136, 163)
Social anxiety disorder	22	5,335	8 (6–12)	(9, 11, 13, 16, 17, 34, 42, 46, 52, 76, 84, 90, 95, 99, 103, 106, 109, 125, 129, 134, 161, 163)	13	1,526	13 (9–16)	(9, 11, 13, 27, 42, 52, 90, 99, 106, 109, 129, 136, 163)
Generalized anxiety disorder	20	4,968	14 (11–19)	(11, 13, 16, 17, 34, 42, 46, 52, 76, 84, 90, 95, 98, 99, 103, 106, 109, 129, 134, 161)	12	1,516	16.6 (14–20)	(11, 13, 27, 42, 52, 90, 98, 99, 106, 109, 129, 136)