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. 2018 Jun 27;9:229. doi: 10.3389/fpsyt.2018.00229

Table 5.

Analysis of possible associated features that may affect the heterogeneity of lifetime anxiety disorder comorbidity in bipolar disorder.

Lifetime Comorbidity
Any anxiety disorder Panic disorder Obsessive compulsive disorder Social anxiety disorder Generalized anxiety disorder
No of Studies p-value No of Studies p-value No of Studies p-value No of Studies p-value No of Studies p-value
% of BD I patients 35 0.43 49 0.99 41 0.31 40 0.33 33 0.85
Mean Age 38 0.87 55 0.82 48 0.01 46 0.98 35 0.49
% of Married patients 17 0.07 23 0.25 18 0.60 22 0.52 17 0.65
% of patients in a manic episode 12 0.03 19 0.08 18 0.006 19 0.02 16 0.80
% with a history of psychosis 12 0.44 22 0.92 20 0.95 21 0.31 14 0.34
% of high school and higher graduates 7 0.28 10 0.22 8 0.28 9 0.30 8 0.17
% of females 37 0.91 54 0.07 46 0.48 45 0.87 35 0.38
Duration of illness 14 0.20 12 0.83 11 0.02 13 0.24 11 0.91
Age of onset 30 0.07 46 0.08 38 0.13 38 0.006 31 0.52
% of patients with ADHD 4 0.001 3 0.001 3 0.00002 3 0.9
% of patients with SUD 30 0.15 46 0.26 38 0.44 35 0.02 28 0.31
Family history of BD 7 0.1 10 0.05 9 0.74 9 0.56 6 0.72

The bold values indicate significant variables.