Table 3.
Rotavirus-Specific Immunoglobulin A Seroconversion and Protection From Rotavirus Diarrhea Through 1 Year of Life
| Group | Seroconversion | No RVD | RVD | RR (95% CI) | P Valueb |
|---|---|---|---|---|---|
| No. (%) GMC [Range]a | No. (%) GMC [Range]a | ||||
| All (N = 564) | Yes | 107 (84.9) | 19 (15.1) | 0.52 (.34–.81) | .002 |
| 108.5 [20.1–7297]c | 57.2 [22.4–1017]c | ||||
| No | 311 (71.0) | 127 (29.0) | |||
| <20 | <20 | ||||
| Vaccinated (n = 279) | Yes | 69 (90.8) | 7 (9.2) | 0.47 (.22–1.00) | .037 |
| 111.1 [20.1–7297] | 77.6 [23.4–1017] | ||||
| No | 163 (80.3) | 40 (19.7) | |||
| <20 | <20 | ||||
| Unvaccinated (n = 285) | Yes | 38 (76.0) | 12 (24.0) | 0.65 (.39–1.09) | .079 |
| 104.1 [20.9–3829]d | 47.9 [22.4–338]d | ||||
| No | 148 (63.0) | 87 (37.0) | |||
| <20 | <20 |
Abbreviations: CI, confidence interval; GMC, geometric mean concentration; RR, relative risk; RVD, rotavirus diarrhea.
aComparison of GMC across groups performed by Mann-Whitney U test.
b P value by χ2 or Fisher exact test.
c P = .054.
d P = .046.