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. 2017 Dec 22;33(7):1129–1137. doi: 10.1093/ndt/gfx332

Table 1.

Impaired renal function in Col4a3^KO mice

Biochemical parameters of renal function	129Sv		B6
Biochemical parameters of renal function	10 weeks		10 weeks		20 weeks
	WT	Col4a3^KO	WT	Col4a3^KO	WT	Col4a3^KO
BUN (mg/dL)	34.1 ± 4.4	190.8 ± 38.6^b	24.9 ± 1.2	41.2 ± 1.9^a	24.0 ± 2.6	85.2 ± 16.9^a
Serum creatinine (mg/dL)	0.27 ± 0.01	1.59 ± 0.40^a	0.40 ± 0.03	1.05 ± 0.05^a	0.50 ± 0.02	1.29 ± 0.11^a
eGFR (µL/min)	39.6 ± 3.9	7.0 ± 1.5^b	43.7 ± 1.7	27.2 ± 5.4^a	45.2 ± 7.5	18.5 ± 1.5^a
ACR (mg/mg)	1.5 ± 0.2	7.4 ± 1.7^b	0.9 ± 0.3	3.6 ± 0.5^a	0.7 ± 0.1	4.0 ± 1.2^a
24-h urine albumin (ug)	149.1 ± 31.4	678.4 ± 175.7^a	205.0 ± 75.9	848.0 ± 281.8^a	222.1 ± 32.6	1450.6 ± 238.9^b

Values are mean ± standard error, n = 5 per group.

P < 0.05 versus ^aWT, ^ball groups.