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. 2017 Dec 22;33(7):1129–1137. doi: 10.1093/ndt/gfx332

Table 2.

Altered mineral metabolism in Col4a3KO mice

Biochemical parameters of mineral metabolism 129Sv
B6
10 weeks
10 weeks
20 weeks
WT Col4a3KO WT Col4a3KO WT Col4a3KO
PTH (pg/mL) 281.5 ± 35.8 2521.6 ± 675.3a 640.8 ± 215.8 770.2 ± 152.9 415.5 ± 62.2 3644.4 ± 1201.8a
1,25(OH)2D (pg/mL) 76.1 ± 14.4 43.0 ± 7.4 164.7 ± 18.1c 170.4 ± 24.7c 197.2 ± 23.5c 203.1 ± 16.7c
Pi (mg/dL) 6.8 ± 0.3 14.1 ± 1.4b 7.0 ± 0.5 7.5 ± 0.8 6.2 ± 0.4 8.9 ± 0.8a
Ca2+ (mg/dL) 10.4 ± 0.2 12.7 ± 1.3a 10.5 ± 0.8 12.1 ± 0.5 7.6 ± 0.2 9.9 ± 0.5a
FePi (%) 6.5 ± 1.7 15.4 ± 2.7a 9.5 ± 2.3 17.3 ± 2.5a 4.8 ± 0.7 12.7 ± 1.9a
FeCa (%) 0.9 ± 0.4 10.6 ± 4.6a 0.9 ± 0.3 1.2 ± 0.1 0.6 ± 0.1 3.6 ± 1.3a

Values are mean  ±  standard error, n  =  5 per group.

P  <  0.05 versus aWT, ball groups and call 129Sv.