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. 2017 Oct 31;34(5):867–868. doi: 10.1093/bioinformatics/btx699

Table 1.

Comparison of depth tools for time and memory use on a 30× BAM

Tool Threads Relative time Time (hh:mm:ss) Memory (MiB)
Mosdepth 1 1 25:23 1196
Mosdepth 3 0.57 14:27 1196
Samtools 1 1.98 50:12 27
Sambamba 1 5.71 2:24:53 166
BEDtools 1 5.31 2:14:44 1908

Note: Mosdepth and BEDTools use much more memory, but mosdepth is nearly twice as fast as the next fastest tool, samtools. The threads column reflects the number of threads for BAM/CRAM decompression.