. 2001 Oct 24;2(11):research0049.1–research0049.12. doi: 10.1186/gb-2001-2-11-research0049

Table 3.

Percentage of random amino-acid frequency assignments yielding lower fractions f than the natural one

	%
g^pol	3
g^access	<1
g^PAM	<1
g^mutate	<1

Percentage of the sets of random amino-acid frequency assignments for which the fraction f of random codes that beat the natural code is lower than the corresponding fraction computed with the natural frequency p(a) values. This percentage is estimated for the four cost functions - g^pol, g^access, g^mutate and g^PAM - on the basis of 100 random frequencies and, for each of them, 10⁶ random codes. For all cost functions except g^pol, we were only able to give an upper bound (estimated to be equal to 1%), because our sample of random codes is too small and we did not find any random frequency set for which f is lower than that obtained with the natural frequencies.