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. 2018 Apr 25;27(14):2502–2516. doi: 10.1093/hmg/ddy154

Figure 5.

Figure 5.

Immunofluorescence analysis of mitochondrial dynamics proteins in HT22 cells transfected with mutant APP cDNA relative to untransfected HT22 cells.Figure 5A presents representative images of immunofluorescence analysis. Figure 5B represents quantitative immunofluorescence analysis. Significantly increased levels of Drp1 (P=0.01), Fis1 (P=0.03) and significantly decreased levels of Mfn1 (P=0.01), Mfn2 (P=0.003) and Opa1 (P=0.01) were found in HT22 cells transfected with mutant APP cDNA relative to untransfected HT22 cells.