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. 2018 Apr 25;27(14):2502–2516. doi: 10.1093/hmg/ddy154

Figure 8.

Figure 8.

Immunofluorescence analysis of mitophagy and autophagy proteins in HT22 cells transfected with mutant APP cDNA relative to untransfected HT22 cells. Figure 8A, presents representative images of immunofluorescence analysis. Figure 8F represents quantitative immunofluorescence analysis. Significantly decreased levels of autophagy proteins ATG5 (P=0.002), LCB3 (P=0.003) and TERT (P=0.01) and mitophagy protein PINK1 (P=0.01) in HT22 cells transfected with mutant APP cDNA relative to untransfected HT22 cells.