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. 2018 May 1;46(Web Server issue):W271–W277. doi: 10.1093/nar/gky349

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Transformation of a single-nucleotide frequency file to a consensus sequence at a prevalence cutoff of 10%. (A) Example of a nucleotide frequency file providing the nucleotide counts for the first three positions in a viral genome. (B) Table of prevalence ratios in which observations with ratios of at least 10% are shown in red. The corresponding motif logo in which the height of individual nucleotides reflects their prevalence is shown below. (C) Consensus sequence constructed for a prevalence cutoff of 10%. Ambiguous positions are encoded according to IUPAC nomenclature.