Table 3.

Prediction performance of PaRSnIP compared with six protein solubility prediction tools

	PaRSnIP	PROSO II	CCSOL	SOLpro	PROSO	RPSP	SCM
Accuracy (%)	74.11	64.35	54.20	59.95	57.85	51.45	59.67
MCC	0.48	0.31	0.08	0.20	0.16	0.03	0.21
Sensitivity (soluble)	0.73	0.46	0.51	0.51	0.54	0.44	0.42
Sensitivity (insoluble)	0.75	0.82	0.57	0.69	0.62	0.59	0.77
Selectivity (soluble)	0.75	0.72	0.54	0.62	0.58	0.52	0.65
Selectivity (insoluble)	0.74	0.60	0.54	0.58	0.57	0.51	0.57
Gain (soluble)	1.50	1.45	1.09	1.24	1.17	1.03	1.30
Gain (insoluble)	1.47	1.21	1.08	1.17	1.15	1.02	1.14

Note: Best performing method in bold. Performance values adopted from Chang et al. (2014).