Table 2.

Unadjusted and adjusted hazard ratios for outcomes at 1 year and 3 years post-discharge among patients with ischaemic stroke

	Cumulative incidence		Unadjusted analysis		Adjusted analysis
	N (%)	P-valuea	HR (95% CI)	P-valueb	HR (95% CI)	P-valueb
At 1 year
All-cause mortality
Diabetes	32 670 (27.00)	0.54	1.00 (0.98–1.01)	0.57	1.20 (1.18–1.22)	<0.0001
No diabetes	77 402 (26.87)		Reference		Reference
All-cause readmission
Diabetes	62 749 (52.61)	<0.0001	1.23 (1.22–1.24)	<0.0001	1.21 (1.20–1.23)	<0.0001
No diabetes	127 971 (44.94)		Reference		Reference
Composite of mortality and all-cause readmission
Diabetes	75 995 (63.63)	<0.0001	1.14 (1.13–1.15)	<0.0001	1.19 (1.18–1.20)	<0.0001
No diabetes	165 843 (58.16)		Reference		Reference
Composite of mortality and CV readmission
Diabetes	56 137 (47.05)	<0.0001	1.10 (1.09–1.11)	<0.0001	1.16 (1.15–1.18)	<0.0001
No diabetes	123 675 (43.38)		Reference		Reference
IS/TIA readmission
Diabetes	11 759 (9.87)	<0.0001	1.20 (1.17–1.23)	<0.0001	1.15 (1.12–1.17)	<0.0001
No diabetes	23 364 (8.21)		Reference		Reference
HF readmission
Diabetes	6653 (5.60)	<0.0001	1.61 (1.56–1.67)	<0.0001	1.55 (1.50–1.61)	<0.0001
No diabetes	9868 (3.47)		Reference		Reference
Non-CV readmission
Diabetes	46 156 (38.77)	<0.0001	1.26 (1.24–1.27)	<0.0001	1.27 (1.26–1.29)	<0.0001
No diabetes	90 851 (31.95)		Reference		Reference
Non-IS/TIA readmission
Diabetes	57 783 (48.47)	<0.0001	1.24 (1.22–1.25)	<0.0001	1.22 (1.21–1.24)	<0.0001
No diabetes	116 608 (40.97)		Reference		Reference
IS readmission
Diabetes	9228 (7.74)	<0.0001	1.22 (1.19–1.25)	<0.0001	1.17 (1.13–1.20)	<0.0001
No diabetes	18 070 (6.34)		Reference		Reference
AMI readmission
Diabetes	2669 (2.24)	<0.0001	1.56 (1.49–1.64)	<0.0001	1.52 (1.45–1.60)	<0.0001
No diabetes	4060 (1.43)		Reference		Reference
At 3 year
All-cause mortality
Diabetes	55 627 (45.98)	<0.0001	1.04 (1.03–1.05)	<0.0001	1.24 (1.23–1.25)	<0.0001
No diabetes	127 320 (44.20)		Reference		Reference
All-cause readmission
Diabetes	83 474 (71.30)	<0.0001	1.22 (1.21–1.24)	<0.0001	1.22 (1.21–1.23)	<0.0001
No diabetes	178 385 (63.74)		Reference		Reference
Composite of mortality and all-cause readmission
Diabetes	98 713 (84.12)	<0.0001	1.15 (1.14–1.16)	<0.0001	1.21 (1.20–1.22)	<0.0001
No diabetes	222 467 (79.28)		Reference		Reference
Composite of mortality and CV readmission
Diabetes	80 991 (69.45)	<0.0001	1.13 (1.12–1.14)	<0.0001	1.19 (1.18–1.20)	<0.0001
No diabetes	179 792 (64.30)		Reference		Reference
IS/TIA readmission
Diabetes	18 499 (15.94)	<0.0001	1.22 (1.20–1.24)	<0.0001	1.18 (1.16–1.20)	<0.0001
No diabetes	36 944 (13.27)		Reference		Reference
HF readmission
Diabetes	11 820 (10.27)	<0.0001	1.64 (1.60–1.68)	<0.0001	1.60 (1.56–1.64)	<0.0001
No diabetes	17 676 (6.39)		Reference		Reference
Non-CV readmission
Diabetes	67 775 (58.30)	<0.0001	1.25 (1.24–1.26)	<0.0001	1.28 (1.26–1.29)	<0.0001
No diabetes	140 119 (50.33)		Reference		Reference
Non-IS/TIA readmission
Diabetes	79 000 (67.62)	<0.0001	1.23 (1.22–1.24)	<0.0001	1.23 (1.22–1.25)	<0.0001
No diabetes	166 898 (59.72)		Reference		Reference
IS readmission
Diabetes	14 589 (12.57)	<0.0001	1.24 (1.21–1.26)	<0.0001	1.20 (1.18–1.23)	<0.0001
No diabetes	28 644 (10.29)		Reference		Reference
AMI readmission
Diabetes	5398 (4.72)	<0.0001	1.62 (1.56–1.67)	<0.0001	1.55 (1.49–1.60)	<0.0001
No diabetes	8136 (2.95)		Reference		Reference

CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; IS, ischaemic stroke; TIA, transient ischaemic attack.

^aLog-rank P-values were presented for mortality outcomes, Gray’s P-values were presented for other outcomes.

^bP < 0.05 indicates that the care differs significantly between those with and without diabetes.