Table 3.
Predictors of one or more red blood cell transfusions during admission for subarachnoid hemorrhage, clustered by center
| Univariate analysis | Multivariable model (n = 463; 95 events) | ||||||
|---|---|---|---|---|---|---|---|
| Variable | OR | 95% CI | p Value | Variable | OR | 95% CI | p Value |
| Age (increase by 10 years) | 1.07 | 0.90–1.28 | 0.458 | Age (increase by 10 years) | 1.06 | 0.78–1.45 | 0.711 |
| Sex (male vs other) | 0.45 | 0.19–1.10 | 0.080 | Sex (male vs other) | 0.84 | 0.45–1.57 | 0.593 |
| Hx of oral AC use | 1.93 | 1.01–3.68 | 0.046 | Hx of Oral AC use | 1.00 | 0.60–1.67 | 0.993 |
| Admission Hb (increase by 10 g/L) | 0.40 | 0.39–0.41 | < 0.0001 | Admission Hb (increase by 10 g/L) | 0.81 | 0.69–0.96 | 0.013 |
| Modified Fisher grade 3–4 vs 0–2a | 1.02 | 0.90–1.15 | 0.765 | Modified Fisher Grade 3–4 vs 0–2a | 1.02 | 0.77–1.36 | 0.876 |
| Anterior circulation (vs posterior) | 1.46 | 1.17–1.83 | 0.001 | Anterior circulation (vs Posterior) | 1.18 | 0.90–1.55 | 0.231 |
| Clip (vs other) | 4.39 | 3.25–5.92 | < 0.0001 | Clip (vs other) | 2.44 | 1.21–4.94 | 0.013 |
| Anemia (Hb ≤100 g/L) | 28.17 | 11.06–71.75 | < 0.0001 | Anemia (Hb ≤100 g/L) | 17.38 | 5.11–59.13 | < 0.0001 |
| Vasospasm (pre-RBCTx) | 1.62 | 0.91–2.88 | 0.100 | Vasospasm (pre-RBCTx) | 1.11 | 0.40–3.09 | 0.845 |
| Cerebral infarct (pre-RBCTx) | 1.08 | 0.96–1.23 | 0.206 | ||||
Abbreviations: AC Anticoagulant, antiplt Antiplatelet, Hb Hemoglobin, Hx History, RBCTx Red blood cell transfusion
aDichotomized as high (3–4) vs low (0–2) grade