Skip to main content
. Author manuscript; available in PMC: 2019 Feb 14.
Published in final edited form as: Cell Host Microbe. 2018 Feb 2;23(2):274–281.e2. doi: 10.1016/j.chom.2017.12.006

Figure 1. Spatial and temporal analysis of V. cholerae colonization.

Figure 1

(A) V. cholerae population size was determined by counting colony forming units (CFU) present per cm of tissue in the proximal (PSI, Green), middle (MSI, Blue), distal (DSI, Red) small intestine, and cecum (Black) at 3, 6, 12, or 18 hr post infection. (B) In vivo competition experiments were performed between strains C6706 tsiV3 vipA (T6SS− and T6SS-sensitive) and parental strain C6706 lacZ (T6SS+). Bacteria were recovered from the MSI or DSI after 3, 6, and 18 hr. Control was a competition between wild type C6706 and C6706 lacZ in DSI after 18 hr. Each data point indicates the competitive index (C.I.) relative to wild type between the two strains for each experimental animal. Bars indicate mean and standard error. Significance was determined relative to the C.I. of the control group (NS - not significant, ** - p < 10−2, *** - p < 10−3, **** - p < 10−4).