Table 4. Randomized Trials Comparing Single versus Multifraction Radiotherapy in Bone Metastases.
Study | Complete pain relief | Overall pain relief | Retreatment | |
---|---|---|---|---|
Bone Trial Working Party Study Group (1999) [14] | 8 Gy single fraction | 57% | 78% | 23% |
20 Gy/5 Fr or 30 Gy/10 Fr |
58% | 78% | 10% | |
Hartsell et al (2005) [17] | 8 Gy single fraction | 15% | 65% | 18% |
30 Gy/10 Fr | 18% | 66% | 9% | |
Roos et al (2005) [18] | 8 Gy single fraction | 26% | 53% | 1% |
20 Gy/5 Fr | 27% | 61% | 0 | |
Arnalot et al (2008) [19] | 8 Gy single fraction | 15% | 75% | 28% |
30 Gy/10 Fr | 13% | 86% | 2% | |
Anter et al (2015) [20] | 8 Gy single fraction | 18% | 75% | - |
20 Gy/5 Fr | 22% | 75% | - |