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. 2018 Jun 26;9(3):91–95. doi: 10.14740/wjon1118w

Table 4. Randomized Trials Comparing Single versus Multifraction Radiotherapy in Bone Metastases.

Study Complete pain relief Overall pain relief Retreatment
Bone Trial Working Party Study Group (1999) [14] 8 Gy single fraction 57% 78% 23%
20 Gy/5 Fr or
30 Gy/10 Fr
58% 78% 10%
Hartsell et al (2005) [17] 8 Gy single fraction 15% 65% 18%
30 Gy/10 Fr 18% 66% 9%
Roos et al (2005) [18] 8 Gy single fraction 26% 53% 1%
20 Gy/5 Fr 27% 61% 0
Arnalot et al (2008) [19] 8 Gy single fraction 15% 75% 28%
30 Gy/10 Fr 13% 86% 2%
Anter et al (2015) [20] 8 Gy single fraction 18% 75% -
20 Gy/5 Fr 22% 75% -