Table 2. The Relationships Between Clinical Characteristics and Each Inflammation-Based Score.
GPS |
NLR |
SII |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
GPS 0 | GPS 1 | GPS 2 | P value | Low | High | P value | Low | High | P value | ||
Age (years old) | < 65 | 68 | 31 | 7 | 0.063 | 98 | 8 | 0.222 | 62 | 44 | 0.276 |
≥ 65 | 123 | 81 | 31 | 225 | 10 | 152 | 83 | ||||
Gender | Male | 83 | 65 | 25 | 0.007 | 158 | 15 | 0.003 | 93 | 80 | 0.001 |
Female | 108 | 47 | 13 | 165 | 3 | 121 | 47 | ||||
Smoking | Never | 109 | 40 | 9 | <0.001 | 154 | 4 | 0.029 | 114 | 44 | 0.001 |
Current/former | 82 | 72 | 29 | 169 | 14 | 100 | 83 | ||||
Histology | Adeno | 163 | 81 | 24 | 0.002 | 258 | 10 | 0.024 | 182 | 86 | < 0.001 |
Others | 28 | 31 | 14 | 65 | 8 | 32 | 41 | ||||
pStage | I | 150 | 91 | 24 | 0.081 | 256 | 9 | 0.008 | 178 | 87 | < 0.001 |
II - III | 41 | 21 | 14 | 67 | 9 | 36 | 40 | ||||
pT status | pT1 | 136 | 82 | 17 | 0.004 | 227 | 8 | 0.027 | 157 | 78 | 0.022 |
pT2-3 | 55 | 30 | 21 | 96 | 10 | 57 | 49 | ||||
pN status | pN0 | 163 | 100 | 29 | 0.162 | 281 | 11 | 0.008 | 192 | 100 | 0.006 |
pN1-2 | 28 | 12 | 9 | 42 | 7 | 22 | 27 | ||||
CEA | Normal | 146 | 84 | 24 | 0.250 | 241 | 13 | 0.822 | 159 | 95 | 0.918 |
High | 45 | 28 | 14 | 82 | 5 | 55 | 32 | ||||
CYFRA | Normal | 166 | 91 | 26 | 0.026 | 272 | 11 | 0.023 | 181 | 102 | 0.314 |
High | 25 | 21 | 12 | 51 | 7 | 33 | 25 |
PLR |
PNI |
ALI |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
PLR 0 | PLR 1 | PLR 2 | P value | PNI 0 | PNI 1 | P value | Low | High | P value | ||
Age | < 65 | 62 | 40 | 4 | 0.084 | 82 | 24 | 0.001 | 37 | 69 | 0.941 |
≥ 65 | 166 | 61 | 8 | 138 | 97 | 83 | 152 | ||||
Gender | Male | 106 | 58 | 9 | 0.040 | 109 | 64 | 0.554 | 73 | 100 | 0.006 |
Female | 122 | 43 | 3 | 111 | 57 | 47 | 121 | ||||
Smoking | Never | 114 | 41 | 3 | 0.086 | 105 | 53 | 0.486 | 43 | 115 | 0.004 |
Current/former | 114 | 60 | 9 | 115 | 68 | 77 | 106 | ||||
Histology | Adeno | 185 | 75 | 8 | 0.235 | 175 | 93 | 0.565 | 82 | 186 | 0.001 |
Others | 43 | 26 | 4 | 45 | 28 | 38 | 35 | ||||
pStage | I | 186 | 73 | 6 | 0.018 | 170 | 95 | 0.792 | 83 | 182 | 0.006 |
II - III | 42 | 28 | 6 | 50 | 26 | 37 | 39 | ||||
pT status | pT1 | 162 | 68 | 5 | 0.111 | 157 | 78 | 0.190 | 76 | 159 | 0.103 |
pT2-3 | 66 | 33 | 7 | 63 | 43 | 44 | 62 | ||||
pN status | pN0 | 203 | 81 | 8 | 0.027 | 191 | 101 | 0.403 | 95 | 197 | 0.014 |
pN1-2 | 25 | 20 | 4 | 29 | 20 | 25 | 24 | ||||
CEA | Normal | 171 | 74 | 9 | 0.946 | 169 | 85 | 0.186 | 87 | 167 | 0.537 |
High | 57 | 27 | 3 | 51 | 36 | 33 | 54 | ||||
CYFRA | Normal | 194 | 80 | 9 | 0.334 | 190 | 93 | 0.028 | 89 | 194 | 0.002 |
High | 34 | 21 | 3 | 30 | 28 | 31 | 27 |
GPS: Glasgow prognostic score; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; PNI: prognostic nutritional index; SII: systemic immune-inflammation index; ALI: advance lung cancer inflammation index; CEA: carcinoembryonic antigen; CYFRA21-1: cytokeratin 19 fragments.