Table 5. Univariate and Multivariate Analysis.

		Univariate			Multivariate
		Regression coefficient (95% CI)		P-value	Regression coefficient (95% CI)		P-value
% change in TC at 24 weeks
Age	≥ 60	0.2	(-4.8, 5.2)	0.94	-1.7	(-6.4, 3.0)	0.47
Sex	Male	4.0	(-0.4, 8.4)	0.075	3.9	(-0.1, 8.0)	0.055
BMI	≥ 25 kg/m2	1.4	(-2.9, 5.8)	0.52	2.4	(-1.9, 6.6)	0.27
Baseline TC	≥ 200 mg/dL	-7.9	(-11.9, -3.8)	< 0.001*	-10.1	(-15.7, -4.6)	< 0.001*
Baseline LDL-C	≥ 120 mg/dL	-5.3	(-9.7, -1.0)	0.016*	1.8	(-3.8, 7.4)	0.53
Baseline HDL-C	≥ 40 mg/dL	-7.4	(-13.8, -1.1)	0.021*	-3.7	(-10.5, 3.2)	0.29
Baseline TG	≥ 150 mg/dL	-0.8	(-5.4, 3.7)	0.73
Lipid therapy	Yes	3.4	(-0.9, 7.7)	0.12
Statin	Yes	0.8	(-3.5, 5.2)	0.71
% change in LDL-C at 24 weeks
Age	≥ 60	2.6	(-6.5, 11.7)	0.58	-1.2	(-9.3, 7.0)	0.78
Sex	Male	7.0	(-0.7, 14.8)	0.075	7.2	(0.3, 14.1)	0.04*
BMI	≥ 25 kg/m2	2.0	(-5.8, 9.8)	0.62	3.1	(-4.1, 10.3)	0.40
Baseline TC	≥ 200 mg/dL	-14.6	(-21.8, -7.4)	< 0.001*	-9.3	(-19.2, 0.6)	0.065
Baseline LDL-C	≥ 120 mg/dL	-12.1	(-19.5, -4.6)	0.002*	-3.9	(-13.7, 5.9)	0.44
Baseline HDL-C	≥ 40 mg/dL	-22.7	(-35.5, -10.0)	< 0.001*	-16.7	(-29.0, -4.4)	0.008*
Baseline TG	≥ 150 mg/dL	5.0	(-3.1, 13.0)	0.23
Lipid therapy	Yes	6.9	(-0.8, 14.5)	0.078
Statin	Yes	6.2	(-1.4, 13.9)	0.11
% change in HDL-C at 24 weeks
Age	≥ 60	3.4	(-2.1, 8.9)	0.22	-1.2	(-9.3, 7.0)	0.78
Sex	Male	-1.2	(-6.4, 4.0)	0.65	7.2	(0.3, 14.1)	0.04*
BMI	≥ 25 kg/m2	-0.1	(-5.1, 4.9)	0.97	3.1	(-4.1, 10.3)	0.40
Baseline TC	≥ 200 mg/dL	-6.1	(-11.1, -1.2)	0.015*	-9.3	(-19.2, 0.6)	0.065
Baseline LDL-C	≥ 120 mg/dL	-3.7	(-8.9, 1.5)	0.17	-3.9	(-13.7, 5.9)	0.44
Baseline HDL-C	≥ 40 mg/dL	-11.6	(-18.9, -4.3)	0.002*	-16.7	(-29, -4.4)	0.008*
Baseline TG	≥ 150 mg/dL	3.4	(-1.7, 8.5)	0.19
Lipid therapy	Yes	0.3	(-4.7, 5.3)	0.92
Statin	Yes	-0.2	(-5.2, 4.8)	0.95

*P < 0.05.