Table 1. Overall Characteristics of Adrenocortical Carcinoma Between 1973 and 2014.
| N (%) | |
|---|---|
| Total cases | 2,014 (100) |
| Year of diagnosis | |
| 1973 - 1984 | 187 (9.3) |
| 1985 - 1994 | 297 (14.7) |
| 1995 - 2004 | 597 (29.7) |
| 2005 - 2014 | 933 (46.3) |
| Gender | |
| Male | 861 (42.8) |
| Female | 1,153 (57.2) |
| Median age at diagnosis | 55 years |
| Age at diagnosis | |
| 00 - 09 years | 77 (3.8) |
| 10 - 19 years | 54 (2.7) |
| 20 - 29 years | 103 (5.1) |
| 30 - 39 years | 213 (10.6) |
| 40 - 49 years | 331 (16.4) |
| 50 - 59 years | 447 (22.2) |
| 60 - 69 years | 447 (22.2) |
| 70 - 79 years | 249 (12.4) |
| 80+ years | 93 (4.6) |
| Race | |
| White | 1,736 (86.2) |
| Black | 142 (7.1) |
| Others | 132 (6.7) |
| Primary malignancy | |
| One primary only | 1,618 (80.3) |
| More than one primary | 396 (19.7) |
| Laterality | |
| Unilateral, right | 874 (43.4) |
| Unilateral, left | 1,040 (51.6) |
| Bilateral | 20 (1) |
| Unknown | 80 (4) |
| Grade of tumor | |
| Well differentiated, grade I | 62 (14.8) |
| Moderately differentiated, grade II | 82 (19.6) |
| Poorly differentiated, grade III | 161 (38.4) |
| Undifferentiated, grade IV | 114 (27.2) |
| Unknown | 1,595 |
| Treatment | |
| Surgery | 1,482 (73.6) |
| Adjuvant radiotherapy | 159 (7.9) |
| Adjuvant chemotherapy | 406 (20.2) |
| Chemotherapy alone | 223 (11.1) |
| Cause specific mortality | |
| Overall | 1,051 (52.2) |
| 1973 - 1984 | 127 (67.9) |
| 1985 - 1994 | 160 (53.9) |
| 1995 - 2004 | 331 (55.4) |
| 2005 - 2014 | 433 (46.4) |
| Median survival | |
| Overall | 17 months |
| 1973 - 1984 | 14 months |
| 1985 - 1994 | 22 months |
| 1995 - 2004 | 28 months |
| 2005 - 2014 | 14 months |