Table 4.
Medical group | Surgical group | |||||||||
Baseline | 6 months | Baseline | 6 months | |||||||
Off-medication | On-medication | Off-medication | On-medication | Off-medication | On-medication | Off-medication off-stimulation |
On-medication off-stimulation |
Off- medication on-stimulation |
On-medication on-stimulation |
|
Tremor (items 20–21) | 8.3±6.4 | 2.1±3.9 | 6.9±5.6 | 2.7±4.7 | 5.1±3.4 | 2.3±4.2 | 6.1±4.6 | 2.1±4.2 | 0.4±0.5 | 0.4±0.8 |
Speech (item 18) | 1.3±0.7 | 0.9±0.5 | 1.2±0.8 | 0.7±0.5 | 1.2±0.7 | 0.8±0.7 | 1.3±0.7 | 1±0.7 | 1.2±0.7 | 0.9±0.6 |
Akinesia (items 22–26) | 15.8±5.6 | 9.1±5.1 | 14.4±4.4 | 7.9±5.4 | 14.3±6.6 | 10±6.1 | 15.7±6.3 | 9.1±3.3 | 9.7±5 | 10.1±6.6 |
Axial (items 27–31) | 4.4±2.4 | 1.4±1.3 | 3.9±2.8 | 1.8±1.8 | 2.8±1.9 | 1.3±1 | 2.4±1.9 | 1.4±1.2 | 2.0±1.4 | 1.8±2.0 |
Dyskinesia | 1.7±2.9 | 1.5±2.6 | 1.5±2.1 | 1.1±0.3 | ||||||
LEDD (mg) | 1043±516 | 1180±548 | 1376±883* | 1054±488* |
Significant P values:
Medical group off-medication vs surgical group off-medication on-stimulation: tremor P=0.001; akinesia: P=0.015.
Surgical group off-medication scores at baseline vs off-medication on-stimulation scores at 6 months: tremor P=0.002; akinesia: P=0.026.
*One patient in surgical group had 8 mg of trihexyphenidyl, both at baseline and at 6 months follow-up.