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. 2018 Jun 13;5:765–770. doi: 10.1016/j.toxrep.2018.06.006

Table 1.

Comparison of various studied antioxidant parameters between 25mg/ml solvent/Kg body weight of Ti-6Al-4V alloy powder and saline treated albino mice of both genders. (N = 6 for each treatment). All values are expressed as mean ± standard deviation. P-value presents the results of 2 sample t-test conducted for each parameter between the two treated groups.

Gender Metabolites Brain
Heart
Liver
Kidney
Lungs
Saline treated
Control
Ti-6Al-4Nb
Treated
P value Saline treated
Control
Ti-6Al-4Nb
Treated
P value Saline treated
Control
Ti-6Al-4Nb
Treated
P value Saline treated
Control
Ti-6Al-4Nb
Treated
P value Saline treated
Control
Ti-6Al-4Nb
Treated
P value
Female Mice Superoxide dismutase (unit/gm) 8.43 ±
0.86
10.73 ±
1
0.1 0.53 ± 0.92 2.37 ± 0.42 0.008** 0.76 ± 0.09 1.7 ± 0.26 0.01** 0.972±
0.36
1.659 ±
0.29
0.2 0.758 ± 0.15 1.203 ± 0.14 0.05*
Malonaldehyde (picomol/gm) 72.0±
7.1
76.6±
6.9
0.7 60.3 ± 18 54.3 ± 12 0.8 36.3 ± 7.0 34.7 ± 5.4 0.9 47.3 ±
7.7
44.3 ±
4.9
0.8 38.90 ±
2.6
44.07 ±
3.9
0.3
Catalase (mg/dL) 31.90± 1.1 34.38 ± 1.8 0.3 30.8± 1.1 29.3 ± 1.0 0.3 12.8 ± 0.47 5.81 ± 1.2 0.001** 32.79 ± 0.89 34.85 ± 2.3 0.4 31.63 ± 1.5 32.40± 1.7 0.8
Male Mice Superoxide dismutase (unit/gm) 6.55 ± 0.58 5.760 ± 0.40 0.3 0.468 ± 0.12 0.463 ± 0.11 1 1.099 ± 0.26 1.271 ± 0.19 0.6 0.460 ± 0.061 0.584 ± 0.057 0.2 2.461 ± 0.20 1.422 ± 0.39 0.05*
Malonaldehyde (picomol/gm) 71.2 ±
9.8
97.5±
9.6
0.09 56.9 ±
13
74.9 ±
11
0.3 35.1 ±
4.4
39.7±
8.7
0.7 54.3 ±
7.9
47.4 ±
11
0.6 38.8 ±
13
43.6 ±
7.8
0.8
Catalase (mg/dL) 34.70± 1.5 30.76± 2.0 0.2 29.53 ±
1.6
26.59 ± 1.4 0.2 18.1 ±
5.5
12.06 ±
3.4
0.4 23.00 ± 3.9 18.74± 4.2 0.5 30.47 ± 0.36 30.93 ± 1.7 0.8

P > 0.05 = Non significant, P < 0.05 = least significant (*), P < 0.01 = significant (**).