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. 2018 Jun 12;11(6):dmm031013. doi: 10.1242/dmm.031013

Fig. 8.

Fig. 8.

Number of dysregulated genes by FC in adult male Ts1Cje, Ts65Dn and Dp(16)1/Yey brains by region. (A-C) Distribution of dysregulated genes in each brain region by FC, showing that the majority of dysregulated genes have small magnitude FCs that lie between 0.75 and 1.25. These genes show a significant FC value in trisomic mice compared with their euploid controls, P<0.05. (A′-C′) Distribution of dysregulated genes that are common to all three models, displayed by brain region. The majority of dysregulated genes in common cluster between 0.8 and 1.3 FC.