Skip to main content
. 2018 Jun 21;131(12):jcs216010. doi: 10.1242/jcs.216010

Fig. 3.

Fig. 3.

Effect of substrate stiffness on intranuclear movement via SINK in monolayers. (A) MSD of intranuclear movement versus lag time (τ) plotted on log-log coordinates for cells in monolayers seeded on glass (green), or collagen coated polyacrylamide gels with elastic moduli of 30, 10 or 2.5 kPa. Intranuclear movement increases as substrate stiffness increases. Error bars represent s.e.m. (B) Comparison of the force generation exponent (β) for monolayers of varying elastic moduli for curves shown in A. *P<0.05 based on the curve fit; error bars represent 95% confidence interval for the fitting of β. Glass, n=84; 30 kPa, n=235; 10 kPa, n=287; 2.5 kPa, n=173.